Nature

Autophagy regulates the cancer stem cell phenotype of head and neck squamous cell carcinoma through the noncanonical FOXO3/SOX2 axis

Autophagy is an essential catabolic process that orchestrates cellular homeostasis and plays dual roles in tumor promotion and suppression. However, the mechanism by which autophagy affects the ...
Nature

Combined effects of hyperthermia and chemotherapy on the regulate autophagy of oral squamous cell carcinoma cells under a hypoxic microenvironment

Autophagy has a complex dual role in tumor survival or cell death owning to that is an evolutionarily conserved catabolic mechanism and provides the cells with a sustainable source of biomolecules and ...
The Conversation

Cells routinely self‑cannibalize to take out their trash, aiding in survival and disease prevention

Illustration of an autophagosome (light blue double-membrane to the right) engulfing cellular material. David S. Goodsell and Daniel Klionsky/RCSB PDB-101, CC BY-SA Don’t let the textbook diagram of a ...
Healthline

6 Signs And Symptoms of Autophagy

Autophagy is a natural cellular process where your body clears out and replaces damaged cell parts with new ones. Fasting, exercising, restricting calories, or following a ketogenic diet can speed up ...