The frequency of disease-related large rearrangements (referred to as copy-number mutations, CNMs) varies among genes, and search for these mutations has an important place in diagnostic strategies.

There is an increasing demand for comprehensive genome analyses of single cells. In cancer genetics, single-cell approaches allow monitoring minimal residual disease or the assessment of heterogeneity ...

Predictors of survival in advanced renal cell carcinoma (RCC): Long-term results from Southwest Oncology Group trial S8949 No significant financial relationships to disclose. This is an ASCO Meeting ...

Array CGH describes a technology in which microarrays comprised of well-defined DNA probes are used to screen DNA test samples to detect changes in sequence copy number. For whole-genome aCGH, genomic ...

Array comparative genomic hybridization (CGH) is illuminating DNA copy number variations (CNV) throughout the genome to diagnose disease etiology and to help tailor treatment regimens for patients to ...