DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Learn how a newly discovered virus disrupts its host’s nucleus in ways that echo how complex cells may have formed billions ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off ...

Danish researchers believe that everyone should monitor their blood folate levels. They argue that a deficiency in folic acid ...