Researchers at Max Planck Florida Institute for Neuroscience have revealed a special input pathway that holds the key to coding sensory information in the Cerebellum As we go about our daily lives, we ...
Optogenetic climbing fiber activation regulates experience-dependent plasticity in the primary somatosensory cortex of mice, suggesting a role of the olivo-cerebellum in instructive signaling across ...
In 1906, Spanish scientist Santiago Ramón y Cajal won the Nobel Prize for his pioneering studies of the microscopic structures of the brain. His famous drawings of Purkinje cells in the cerebellum ...
Joseph Chaumont, Nicolas Guyon, Antoine M. Valera, Guillaume P. Dugué, Daniela Popa, Paikan Marcaggi, Vanessa Gautheron, Sophie Reibel-Foisset, Stéphane Dieudonné ...
Cerebellar rhythm loss due to climbing fiber regression is a shared pathophysiology of motor deficits across cerebellar ...
Progranulin derived from Purkinje cells (PCs) counteracts synapse elimination and reinforces the strongest (winner) climbing fiber (CF). Progranulin acts on developing CF synapses from Postnatal day ...
Cerebellum highlighted in orange with magnified close-up of cerebellar Purkinje cells. Cerebellar means "relating to the cerebellum." Source: Kateryna Kon/Shutterstock In the mid-1970s, my ...
Though there is a wealth knowledge supporting the idea that sensory cues benefit motor learning, the precise brain circuitry and mechanisms tying these two together has been debated in recent years.
Although the prevailing wisdom among neuroscientists is that Purkinje cells have just one primary dendrite that connects with a single climbing fiber from the brain stem, new research shows that ...
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