Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing: the first line of defense against ...
The mammalian complement system is a phylogenetically ancient cascade system that has a major role in innate and adaptive immunity. Activation of component C3 (1,641 residues) is central to the three ...
Figure 1: Domain architecture and structure of C3 and the C3b/C3c:CRIg complexes. Figure 2: CRIg binds to the β-chain of C3b and C3c and inhibits the AP C3 and C5 convertases. Figure 4: CRIg inhibits ...
A complement blood test checks for autoimmune diseases or other issues with your immune system. Your doctor might test you if you have a family history of certain conditions, such as rheumatoid ...
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