Randomized controlled trials have generally shown a benefit from accelerated radiotherapy in head and neck squamous cell carcinoma (HNSCC). However, the large randomized United Kingdom trial CHART ...

There is growing enthusiasm in the pharmaceutical industry for whole-system functional assays that reveal the action of potential drugs on integrated systems such as intact cells in order to find ...

This study was conceived and guided by Prof. Ren Xiang Tan (Nanjing University). To tackle the challenging issues, the reaction flux derailing (RFD) approach was conceptualized, designed, and deployed ...

A fundamental challenge in drug development is the balance between optimizing a drug's lock-and-key fit with its target and the drug's ability to make its way across the cellular membrane and access ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Axcella (Nasdaq: AXLA), a clinical-stage biotechnology company pioneering a new approach to treat complex diseases and improve health using endogenous metabolic ...

The storage and retrieval of information encoded in the nervous system are often accompanied by morphological changes in the participating neurons. During brain development, neurite elongation and ...

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells. While islet transplantation has demonstrated promise, its widespread ...