During her chemistry Nobel Prize lecture in 2018, Frances Arnold said, “Today we can for all practical purposes read, write, and edit any sequence of DNA, but we cannot compose it.” That isn’t true ...

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...

The world of protein engineering just took a giant leap forward. A team in China has developed a method that makes designing better proteins faster, cheaper, and easier. Led by Professor Gao Caixia ...

In a remarkable leap forward for synthetic biology, the AI model ESM3, developed by Evolutionary Scale, has achieved a significant milestone. By simulating half a billion years of evolutionary ...

It has long been thought that protein function and stability are highly sensitive to changes in the composition of the internal structures, or protein cores. However, a large-scale experiment probing ...

Enzymes in laundry detergents, insulin for diabetes, and the antibodies and enzymes used in medicine: all of these exist thanks to protein science and engineering. Protein engineering has transformed ...

Advances in artificial intelligence-assisted protein engineering are enabling breakthroughs in protein design, but they also introduce biosecurity challenges related to potential production of harmful ...