We propose to generate high-density whole genome maps in nano-channels by combining Cas9- guide-RNA (gRNA) sequence-specific DNA labeling and motif-based DNA labeling. Cas9-guide- RNA (gRNA) DNA ...

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

Roland Siezen and colleagues at the University of Nijmegen, the Netherlands, have created a software tool that's long overdue. Most researchers in the eukaryotic model organism community have genome ...

Scientists created the largest functional map of a brain to date using a piece of a mouse's brain. The map details the wiring that connects neurons, offering insight into brain function and ...

An international consortium of scientists reported the completion of a first draft of the bovine genome sequence in October. In a separate announcement, New Zealand-based BoviQuest reported it has ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

A research team uncovered the most comprehensive genomic landscape to date for the kiwifruit genus Actinidia, constructing a super pan-genome based on 14 haplotype-resolved genomes. The study ...

Passing yet another milestone in the rapidly advancing science of genetics, biologists said yesterday that they had compiled a map of the hereditary instructions of the laboratory mouse, the single ...

Life begins with a quiet but precise choreography inside the nucleus. For decades, scientists believed that a newly ...