March 31, 2010 — A blood test may soon be able to identify which patients with multiple sclerosis will and will not respond to beta interferon. Only a reported two-thirds of patients with ...
Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in ...
The 2024 Albert Lasker Award for Basic Medical Research is awarded to Zhijian (James) Chen for his landmark discoveries that explain how DNA stimulates immune responses. DNA is best known as genetic ...
During an initial immune response, interferon gamma prompts macrophages to unwrap specific sections of their DNA to form specialized "enhancer" domains that promote gene activity. These newly formed ...
Higher baseline expression of interferon (IFN)-driven genes was tied to a better response to methotrexate in patients with juvenile idiopathic arthritis (JIA). Gene enrichment in the IFN-alpha (type I ...
In 2015, a virus most people had never heard of suddenly made headlines around the world. Zika virus (ZIKV), long considered a mild mosquito-borne pathogen, was linked to devastating birth defects and ...