Preclinical results indicate new approach could be a way to deliver treatment directly to tumors at higher doses, while reducing side effects in healthy tissue.

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more ...

Researchers developed a chimeric cancer drug that links an Aurora kinase A inhibitor to a tumor-targeting molecule. In ...

Many cancers involve upregulation of Aurora kinase B, which helps deregulate normal cell cycling to drive tumor proliferation. The kinase should therefore be a good therapeutic target, yet no ...

Protein kinase inhibitors represent a major advance in cancer treatment due to their ability to target the specific kinases involved in tumor growth and survival. More than 80 small-molecule protein ...

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more ...