Dimers of the molecular motor kinesin can ‘walk’ along microtubules. A flexible neck connects the head of one kinesin of the dimer to its partner. When one head is bound to a microtubule, and when ...
Inside mammalian cells, kinesin plays the same role as do trucks and locomotives within our countries: it is the main driving force behind the transport of manufactured goods. No wheels are involved, ...
Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?
A toddler running sometimes loses footing because both feet come off the ground at the same time. Kinesin motors that move materials around in cells have the same problem, which limits how fast they ...
Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...
It’s a scientist’s dream to observe proteins in motion: an enzyme wrapping snuggly around its substrate, or a motor protein skipping along the cytoskeleton. But tools to visualize these subtle ...
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