Single-molecule fluorescence spectroscopy has emerged as a transformative technique in the study of biomolecular structure and dynamics. By utilising individual fluorescent probes, this approach ...
What is Fluorescence Correlation Spectroscopy (FCS)? Fluorescence correlation spectroscopy (FCS) is a powerful analytical technique that enables the study of dynamic processes and interactions at the ...
A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...
Gene expression studies can monitor biological processes using a “molecular beacon” (single-stranded DNA, ssDNA), a hairpin-shaped oligonucleotide containing a fluorophore (donor) and a quencher ...
Explore how time-resolved fluorescence enables sensitive monitoring of dye–protein binding in microliter volumes.
RIKEN researchers have demonstrated a method that can detect tiny amounts of biomarkers in liquid samples and can distinguish ...
Force spectroscopy relies on the precise measurement of forces acting on a probe as it interacts with a sample. The key principles of force spectroscopy include: AFM-based force spectroscopy is the ...
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