Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...

The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But ...

Post-thrombotic syndrome is common after deep-vein thrombosis and can cause severe symptoms involving the limbs that impair patients’ activity and quality of life. Endovascular therapy can ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 5).

A carefully planned and executed strategy for system integration can yield greater operational efficiency, meaningful ...

A decade’s worth of public data from hospitals in Madrid suggests that value-based hospital outsourcing is associated with improved clinical outcomes, greater efficiency, and increased patient ...

The Trump administration’s wide-ranging actions to dismantle U.S. environmental regulations will cause long-lasting health harms, disproportionately affecting low-income and other vulnerable groups.

The parents of Terri Schiavo, a Florida woman who was in a persistent vegetative state, objected to her husband's decision to discontinue artificial nutrition, and a protracted legal battle ensued.

Health worker burnout, exacerbated by Covid-19, is not only about long hours. It’s about the fundamental disconnect between health workers and the mission to serve that motivates them.

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 2).

An 18-year-old man presented to the emergency department with generalized tonic–clonic seizures. MRI of the head showed numerous well-defined cystic lesions in the brain that were consistent with ...

Large numbers of patients are already using AI tools to obtain medical advice. Rigorous trials of these tools will be important. But what will they be measured against?