Astrocyte NF-κB activation triggers harmful inflammation and poorer recovery after traumatic brain injury, finds study

A fall on the head, a blow to the skull, or a road traffic accident—the causes of traumatic brain injury are diverse, but the ...
EurekAlert!

Nobel Laureate David Baltimore reviews NF-κB research: Mastering cell fate, regulating health and disease

The diagram depicts negative feedback mechanisms via IκB proteins and A20 in the canonical pathway, and IKKα onto NIK in the non-canonical pathway. There are cross-talk mechanisms such as NIK ...
News Medical

NF-κB activation during COVID-19 and its impact on patients with hypertension

In a recent study published in the journal Hypertension Research, researchers review the role of nuclear factor kappa B (NF-κB) activation in the replication of the severe acute respiratory syndrome ...
Informationsdienst Wissenschaft

Aggravated neuroimmune response, delayed wound healing - NF-κB in astrocytes critically affects traumatic brain injury

Traumatic brain injuries often lead to complications with long-lasting consequences on memory, concentration and movement control. Detrimental secondary inflammatory reactions at the injured tissue ...
GEN

Novel Mechanism in DNA Damage Unraveled

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...