Future Microbiol. 2013;8(11):1431-1451. Bacterial contact with the platelets is a key event for the pathogenesis of sepsis, as deduced from the correlation between sepsis outcome and decreased ...

Cancer researchers report that blood platelets blunt the immune response to cancer. Genetic inactivation of platelets improved the ability of T cells to fight melanoma in preclinical tests. Adoptive T ...

Although cardiac stem cell therapy is a promising treatment for heart attack patients, directing the cells to the site of an injury – and getting them to stay there – remains challenging. In a new ...

A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only a key molecule in blood clotting, ...

SAN DIEGO, Dec 10 (Reuters) - Scientists have for the first time created blood platelet cells by reprogramming stem cells derived from adult cells, offering the potential for a renewable supply of the ...

As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don’t need to and can cause major issues such as strokes and cardiovascular ...

PlateletBio, a company developing a new class of cell therapies based on the biology of platelets, has raised $75.5 million to advance its drug pipeline, including a lead candidate for a rare bleeding ...

Platelets are small discoid anuclear cell fragments that are key players in haemostasis – a frontline physiological response to acute tissue injury. Under basal conditions, platelets circulate at ...

Despite being acaryote cell fragments, platelets share a number of properties of host defense with their big nucleated relatives and represent important elements in innate immunity. For these purposes ...

Platelets promote immune tolerance to certain cancers by suppressing T cells and adoptive T cell therapy may be enhanced by adding antiplatelet drugs, report researchers at the Medical University of ...

When a vascular injury occurs, platelets in young mice form much smaller blood clots (left) than platelets in old mice (right), where the clot almost blocks the blood vessel. Fluorescence microscopy ...