The skin has two types of adult stem cells: epidermal and hair follicle. Their jobs seem well-defined: maintaining the skin, or maintaining hair growth. But as research from Rockefeller University has ...

A challenge in the computational design of enzymes is that multiple properties, including substrate binding, transition state stabilization and product release, must be simultaneously optimized, and ...

Rockefeller scientists uncovered how hair follicle stem cells can switch from growing hair to repairing skin when nutrients run low. The key lies in serine, an amino acid that activates a stress ...

Study: Dual impacts of serine/glycine-free diet in enhancing antitumor immunity and promoting evasion via PD-L1 lactylation. Image Credit: Lightspring/Shutterstock ...

One of the crucial steps in cancer proliferation is evading killer immune cells. Cancer cells use a variety of signaling molecules to evade the immune system. Immune checkpoint inhibitor (ICI) therapy ...

D-serine as an adjunctive treatment did not outperform placebo overall in patients with major depressive disorder (MDD), a new trial showed. However, depressive symptoms and anhedonia were ...

D-serine is a representative D-form amino acid and has crucial roles in mammals, but its role in non-mammals is unclear. Researchers from Japan recently uncovered a functional role of D-serine in a ...

If serine racemase is the magician that for decades disguised its trick—inverting an amino acid to assist learning and memory but also levitate risks of Alzheimer's and stroke—chemists just snuck a ...

A dietary supplement believed to protect against Alzheimer's disease might instead be potentially harmful to the brain, a new study warns. L-serine is an amino acid that serves many different roles in ...