Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by enabling improved scalability and purity.
Fortunately, these giant rings are about to become a lot easier to access. Helma Wennemers and her team at ETH Zurich have ...
A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...
Vapourtec's Peptide-Builder, a fully automated, high-throughput benchtop peptide synthesizer, has been designed to redefine solid-phase peptide synthesis (SPPS). Compact, efficient and intuitive, it ...
The Peptide-ExplorerLT ™ is designed for scientists who need to optimize and explore linear peptide synthesis. The product is a high-spec flow chemistry system that uses continuous flow. The product ...
A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully automated solid phase peptide synthesis. The process begins with swelling ...
Cyclic peptides offer enhanced stability and bioavailability, but precise cyclization strategies and specialized synthetic techniques are required to maintain their biological activity. A recent ...
Amide Technologies has raised $16.5 million in venture capital to help commercialize its peptide production process. The process was developed from 2011 to 2017 in the lab of the Massachusetts ...
Peptide bonds represent a cornerstone in molecular biology. They act as essential chemical linkages that bind amino acids into complex chains, ultimately forming peptides and proteins. These ...