EurekAlert!

UMMS researchers isolate gene mutations in patients with inherited amyotrophic lateral sclerosis

WORCESTER, Mass. — Researchers at the University of Massachusetts Medical School (UMMS) have discovered a new gene whose mutations cause familial amyotrophic lateral sclerosis (ALS), a fatal ...
EurekAlert!

Study identifies new gene associated with ALS

BOSTON – A collaborative research effort spanning nearly a decade between researchers at Massachusetts General Hospital (MGH) and King’s College London (KCL) has identified a novel gene for inherited ...
ALZFORUM

Where’s the FUS?—Evidence for Sporadic ALS Role Creates Stir

Although most cases of amyotrophic lateral sclerosis have no evidence of inheritance, scientists are finding valuable clues to the disease among familial cases. The latest evidence transitioning from ...
ALZFORUM

London, Ontario: The Fuss About FUS at ALS Meeting

As neurologists and neurobiologists gathered for the Third International Research Workshop on Frontotemporal Dementia in ALS, 21-25 June in London, Ontario, Canada, the big buzz was all about Fused in ...
JSTOR Daily

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS

Protein misfolding and mislocalization are common themes in neurodegenerative disorders, including motor neuron disease, and amyotrophic lateral sclerosis (ALS). Maintaining proteostasis is a ...