Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Jacqulyne Robichaux works for MD Anderson Cancer Center. She receives funding from the NIH, CPRIT, Takeda Pharmaceuticals and Spectrum Pharmaceuticals. She is also an inventor on patents held by MD ...

This goes against one of the key assumptions of the theory of evolution. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Genetic changes that ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

Publication bias in translational research and number of polymorphisms analyzed in genetic association studies. Background: Germ line mutations in the base excision repair MUTYH gene were recently ...