The development of robust clinical trial methodologies increasingly relies on advanced statistical frameworks for model selection and the characterisation of dose–response relationships. With modern ...

Stylized curves that illustrate the linear, threshold, and hormetic dose-response models for carcinogens. The central pillar upon which toxicological assessments are built is the dose-response ...

This is a preview. Log in through your library . Abstract This paper introduces a dose-response model for toxic quantal response data based on hit theory applied to the dose unit as transformed by a ...

A dose-response curve is the graphical representation of a dose-response relationship, the magnitude of response of an organism from exposure to drugs and chemical interactors. Usually, dose is ...

An environmental toxicologist who has been an outspoken critic of the current linear no-threshold (LNT) approach to risk assessment for radiation and toxic chemicals, now proposes a new approach ...

Radiation Research, Vol. 158, No. 4 (Oct., 2002), pp. 418-423 (6 pages) Several authors have suggested that there is an excess risk of hyperparathyroidism, adenomas or hyperplasia after exposure to ...

Objective To identify the optimal dose and type of physical activity to improve functional capacity and reduce adverse events in acutely hospitalised older adults. Design Systematic review and ...

With bipartisan support, the US House Science, Space, and Technology Committee recently passed a bill to revitalize low-dose radiation research. The bill, which would authorize an estimated $96 ...

AMHERST, Mass. - Edward Calabrese, the University of Massachusetts Amherst environmental toxicologist who has been an outspoken critic of the current linear no-threshold (LNT) approach to risk ...