This study is led by Dr. Yong Tao (Institute of Microbiolocy, Chinese Academy of Sciences), Dr. Weifeng Liu (Institute of Microbiolocy, Chinese Academy of Sciences) and Dr. Bo Liu (Microcyto Co. Ltd., ...
If you took biochemistry classes, chances are good you remember memorizing the Krebs cycle, a well-known metabolic pathway in which sugars are converted through a series of steps to generate ATP, a ...
Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...
Researchers have new insights into the citric acid cycle: Certain bacteria can use this central metabolic pathway 'backwards', but to do so they must have very high concentrations of the enzyme ...
Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...
The Role of Succinate and the Krebs Cycle One key discovery was a bottleneck in the Krebs cycle, specifically in the production of succinate, a molecule crucial for generating ATP—the primary energy ...