Since the discovery of the CFTR gene in 1989, more than 2,500 mutations have been identified. Cystic fibrosis is caused by mutations in the CFTR gene, which encodes a chloride channel …

Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. [5][6] Geneticist Lap-Chee Tsui and …

The CFTR protein is a particular type of protein called an ion channel. In the lung, the CFTR ion channel moves chloride ions from inside the cell to outside the cell.

The CFTR gene provides instructions for making a protein called the CF transmembrane conductance regulator (CFTR). This protein functions as a channel across the membrane of …

Nov 13, 2025 · Complete information for CFTR gene (Protein Coding), CF Transmembrane Conductance Regulator, including: function, proteins, disorders, pathways, orthologs, and …

Sep 16, 2024 · The cystic fibrosis transmembrane conductance regulator (CFTR) is a complex protein that helps maintain fluid balance in several organs. Mutations in the CFTR protein can …

Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in a gene encoding a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

To avoid confusion with the previously named CF antigen (123885), Riordan et al. (1989) referred to the protein as cystic fibrosis transmembrane conductance regulator (CFTR).

Welcome to the Cystic Fibrosis Mutation Database (CFTR1), devoted to the collection of mutations in the CFTR gene for the international cystic fibrosis genetics research community.

Mar 22, 2023 · The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel that regulates salt and fluid homeostasis across epithelial membranes1.