The New England Journal of Medicine | Research & Review Articles …
The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of ...
Overall Survival with Pembrolizumab in Early-Stage Triple …
Sep 15, 2024 · We randomly assigned, in a 2:1 ratio, patients with previously untreated stage II or III triple-negative breast cancer to receive neoadjuvant therapy with four cycles of pembrolizumab (at a dose ...
Primary Central Nervous System Vasculitis | NEJM
Sep 18, 2024 · Primary CNS vasculitis has had an estimated annual incidence of 2.4 cases per 1 million person-years in Olmsted County, Minnesota. The disorder affects persons of all ages, and its prevalence is ...
Empagliflozin in Patients with Chronic Kidney Disease
Nov 4, 2022 · We enrolled patients with chronic kidney disease who had an estimated glomerular filtration rate (eGFR) of at least 20 but less than 45 ml per minute per 1.73 m 2 of body-surface area, or who had ...
Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in …
Sep 15, 2024 · With a minimum follow-up of 10 years, median overall survival was 71.9 months with nivolumab plus ipilimumab, 36.9 months with nivolumab, and 19.9 months with ipilimumab.
Acetazolamide in Acute Decompensated Heart Failure with …
Aug 26, 2022 · Current guidelines recommend the use of intravenous loop diuretics to ameliorate symptoms of fluid overload in patients with acute decompensated heart failure. 1 Despite the use of high-dose loop ...
Case 18-2021: An 81-Year-Old Man with Cough, Fever, and …
Jun 16, 2021 · An 81-year-old man presented with fever, cough, and shortness of breath. Within a few hours after presentation, chest pain and respiratory distress developed. A chest radiograph showed bilateral pa...
Ponsegromab for the Treatment of Cancer Cachexia
Sep 14, 2024 · In this phase 2, randomized, double-blind, 12-week trial, we assigned patients with cancer cachexia and an elevated serum GDF-15 level (≥1500 pg per milliliter) in a 1:1:1:1 ratio to receive ...
Durvalumab after Chemoradiotherapy in Limited-Stage Small-Cell …
Sep 13, 2024 · Small-cell lung cancer is an aggressive cancer that accounts for approximately 15% of all lung tumors. 1 Approximately one third of patients who receive a diagnosis of small-cell lung cancer ...
Ribociclib plus Endocrine Therapy in Early Breast Cancer
Mar 20, 2024 · The established benefit that was observed with ribociclib in advanced breast cancer prompted its investigation in early breast cancer. The NATALEE trial is a phase 3 trial comparing ribociclib ...