Video: Loop of Henle - Video Explanation! | Osmosis | Osmosis
Video: Loop of Henle - Video Explanation! | Osmosis | Osmosis
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Classify Rx on Instagram: "💊 Loop Diuretics in Anuria - Ineffective & Contraindicated ⚡ Why Ineffective in Anuria 📍 No tubular delivery: Loop diuretics must be secreted into tubular lumen via organic anion transporters in proximal tubule to reach their site of action (thick ascending limb of loop of Henle) - anuria means no urine flow, so drug cannot reach target site 📍 Requires functioning nephrons: Loop diuretics work by blocking Na-K-2Cl cotransporter - if complete renal shutdown (anuria =
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