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“It Didn’t Work on Me” #why. Source- https://doi.org/10.1186/s13073-026-01630-0 A recent study published in Genome Medicine reveals that genetic variants in the PAM gene, present in roughly ten percent of the population, can significantly reduce a person's response to GLP-1 medications. The PAM gene produces an enzyme responsible for activating metabolic hormones. Researchers discovered that individuals with these specific variations actually have higher circulating levels of the hormone but exh
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Were you aware of the role genes like p53 play in cancer prevention? Dr. Patrick Soon-Shiong explains that the body has a gene called p53, which plays a role in helping prevent cancer from developing. He highlights that elephants have multiple copies of this gene, which is one reason they are thought to have lower cancer rates. He also suggests that certain illnesses may affect how this gene functions, though research in this area is still developing. Credit/: Dr. Patrick Soon-Shiong
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